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| 1. | A Laing distal myopathy–associated proline substitution in the β-myosin rod perturbs myosin cross-bridging activity | Massimo Buvoli, Genevieve C.K. Wilson, Ada Buvoli, Jack F. Gugel, Abbi Hau, Carsten G. Bönnemann, Carmen Paradas, David M. Ryba, Kathleen C. Woulfe, Lori A. Walker, Tommaso Buvoli, Julien Ochala, Leslie A. Leinwand | |
| 2. | Complement regulation in the eye: implications for age-related macular degeneration | Georgia A. Wilke, Rajendra S. Apte | |
| 3. | Cirbp suppression compromises DHODH-mediated ferroptosis defense and attenuates hypothermic cardioprotection in an aged donor transplantation model | Yifan Zhu, Chenyu Jiang, Jian He, Chen He, Xingliang Zhou, Xu Huang, Yi Shen, Liwei Wu, Yongnan Li, Bei Feng, Yi Yan, Jun Li, Hao Zhang, Yiwei Liu | |
| 4. | Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling | Emma L. Robinson, Charles A. Tharp, Rushita A. Bagchi, Timothy A. McKinsey | |
| 5. | Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses | Fan Huang, Christophe Gonçalves, Margarita Bartish, Joelle Rémy-Sarrazin, Mark E. Issa, Brendan Cordeiro, Qianyu Guo, Audrey Emond, Mikhael Attias, William Yang, Dany Plourde, Jie Su, Marina Godoy Gimeno, Yao Zhan, Alba Galán, Tomasz Rzymski, Milena Mazan, Magdalena Masiejczyk, Jacek Faber, Elie Khoury, Alexandre Benoit, Natascha Gagnon, David Dankort, Fabrice Journe, Ghanem E. Ghanem, Connie M. Krawczyk, H. Uri Saragovi, Ciriaco A. Piccirillo, Nahum Sonenberg, Ivan Topisirovic, Christopher E. Rudd, Wilson H. Miller Jr., Sonia V. del Rincón | |
| 6. | Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation | Theresa Failer, Michael Amponsah-Offeh, Aleš Neuwirth, Ioannis Kourtzelis, Pallavi Subramanian, Peter Mirtschink, Mirko Peitzsch, Klaus Matschke, Sems M. Tugtekin, Tetsuhiro Kajikawa, Xiaofei Li, Anne Steglich, Florian Gembardt, Annika C. Wegner, Christian Hugo, George Hajishengallis, Triantafyllos Chavakis, Andreas Deussen, Vladimir Todorov, Irakli Kopaliani | |
| 7. | CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication | Pablo Tebas, Julie K. Jadlowsky, Pamela A. Shaw, Lifeng Tian, Erin Esparza, Andrea L. Brennan, Sukyung Kim, Soe Yu Naing, Max W. Richardson, Ashley N. Vogel, Colby R. Maldini, Hong Kong, Xiaojun Liu, Simon F. Lacey, Anya M. Bauer, Felicity Mampe, Lee P. Richman, Gary Lee, Dale Ando, Bruce L. Levine, David L. Porter, Yangbing Zhao, Don L. Siegel, Katharine J. Bar, Carl H. June, James L. Riley | |
| 8. | Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae | Aaron L. Hecht, Lisa C. Harling, Elliot S. Friedman, Ceylan Tanes, Junhee Lee, Jenni Firrman, Fuhua Hao, Vincent Tu, LinShu Liu, Andrew D. Patterson, Kyle Bittinger, Mark Goulian, Gary D. Wu | |
| 9. | A therapeutic leap: how myosin inhibitors moved from cardiac interventions to skeletal muscle myopathy solutions | Julius Bogomolovas, Ju Chen | |
| 10. | A step closer to understanding how a diet high in simple carbohydrates may cause dysbiosis | Shrinivas Bishu, John Y. Kao | |
| 11. | Therapeutic vaccines for herpesviruses | Jeffrey I. Cohen | |
| 12. | Adult and neonatal models of chemogenetic heart failure caused by oxidative stress | Fotios Spyropoulos, Apabrita Ayan Das, Markus Waldeck-Weiermair, Shambhu Yadav, Arvind K. Pandey, Ruby Guo, Taylor A. Covington, Venkata Thulabandu, Kosmas Kosmas, Benjamin Steinhorn, Mark A. Perrella, Xiaoli Liu, Helen Christou, Thomas Michel | |
| 13. | IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis | Yukun Guan, Brandon Peiffer, Dechun Feng, Maria A. Parra, Yang Wang, Yaojie Fu, Vijay H. Shah, Andrew M. Cameron, Zhaoli Sun, Bin Gao | |
| 14. | Life-saving effect of pulmonary surfactant in premature babies | J. Usha Raj, Richard D. Bland, Jahar Bhattacharya, Marlene Rabinovitch, Michael A. Matthay | |
| 15. | BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system | Sabine Schneider, Jessica B. Anderson, Rebecca P. Bradley, Katherine Beigel, Christina M. Wright, Beth A. Maguire, Guang Yan, Deanne M. Taylor, J. William Harbour, Robert O. Heuckeroth | |
| 16. | Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles | Peter Ruzanov, Valentina Evdokimova, Manideep C. Pachva, Alon Minkovich, Zhenbo Zhang, Sofya Langman, Hendrik Gassmann, Uwe Thiel, Marija Orlic-Milacic, Syed H. Zaidi, Vanya Peltekova, Lawrence E. Heisler, Manju Sharma, Michael E. Cox, Trevor D. McKee, Mark Zaidi, Eve Lapouble, John D. McPherson, Olivier Delattre, Laszlo Radvanyi, Stefan E.G. Burdach, Lincoln D. Stein, Poul H. Sorensen | |
| 17. | Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality | Jeremy P. Gygi, Cole Maguire, Ravi K. Patel, Pramod Shinde, Anna Konstorum, Casey P. Shannon, Leqi Xu, Annmarie Hoch, Naresh Doni Jayavelu, Elias K. Haddad, IMPACC Network, Elaine F. Reed, Monica Kraft, Grace A. McComsey, Jordan P. Metcalf, Al Ozonoff, Denise Esserman, Charles B. Cairns, Nadine Rouphael, Steven E. Bosinger, Seunghee Kim-Schulze, Florian Krammer, Lindsey B. Rosen, Harm van Bakel, Michael Wilson, Walter L. Eckalbar, Holden T. Maecker, Charles R. Langelier, Hanno Steen, Matthew C. Altman, Ruth R. Montgomery, Ofer Levy, Esther Melamed, Bali Pulendran, Joann Diray-Arce, Kinga K. Smolen, Gabriela K. Fragiadakis, Patrice M. Becker, Rafick P. Sekaly, Lauren I.R. Ehrlich, Slim Fourati, Bjoern Peters, Steven H. Kleinstein, Leying Guan | |
| 18. | A pipeline for senolytics | Sundeep Khosla | |
| 19. | Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction | Kyle Vaccaro, Juliet Allen, Troy W. Whitfield, Asaf Maoz, Sarah Reeves, José Velarde, Dian Yang, Anna Meglan, Juliano Ribeiro, Jasmine Blandin, Nicole Phan, George W. Bell, Aaron N. Hata, Kipp Weiskopf | |
| 20. | Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain | Sonny R. Elizaldi, Chase E. Hawes, Anil Verma, Yashavanth Shaan Lakshmanappa, Ashok R. Dinasarapu, Brent T. Schlegel, Dhivyaa Rajasundaram, Jie Li, Blythe P. Durbin-Johnson, Zhong-Min Ma, Pabitra B. Pal, Danielle Beckman, Sean Ott, Reben Raeman, Jeffrey Lifson, John H. Morrison, Smita S. Iyer | |
| 21. | An in vivo screening platform identifies senolytic compounds that target p16INK4a+ fibroblasts in lung fibrosis | Jin Young Lee, Nabora S. Reyes, Supriya Ravishankar, Minqi Zhou, Maria Krasilnikov, Christian Ringler, Grace Pohan, Chris Wilson, Kenny Kean-Hooi Ang, Paul J. Wolters, Tatsuya Tsukui, Dean Sheppard, Michelle R. Arkin, Tien Peng | |
| 22. | TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation | Hong Li, J. Alyce Bradbury, Matthew L. Edin, Artiom Gruzdev, Huiling Li, Joan P. Graves, Laura M. DeGraff, Fred B. Lih, Chiguang Feng, Erin R. Wolf, Carl D. Bortner, Stephanie J. London, Matthew A. Sparks, Thomas M. Coffman, Darryl C. Zeldin | |
| 23. | STINGing away the pain: the role of interferon-stimulated genes | Erick J. Rodriguez-Palma, Heather N. Allen, Rajesh Khanna | |
| 24. | Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice | Manon Defaye, Amyaouch Bradaia, Nasser S. Abdullah, Francina Agosti, Mircea Iftinca, Mélissa Delanne-Cuménal, Vanessa Soubeyre, Kristofer Svendsen, Gurveer Gill, Aye Ozmaeian, Nadine Gheziel, Jérémy Martin, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Lilian Basso, Emmanuel Bourinet, Isaac M. Chiu, Christophe Altier | |
| 25. | Enhancing anticancer activity of macrophages through rational drug combinations | Gordon B. Mills, Marilyne Labrie | |
| 26. | Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis | Sangsu Bang, Changyu Jiang, Jing Xu, Sharat Chandra, Aidan McGinnis, Xin Luo, Qianru He, Yize Li, Zilong Wang, Xiang Ao, Marc Parisien, Lorenna Oliveira Fernandes de Araujo, Sahel Jahangiri Esfahani, Qin Zhang, Raquel Tonello, Temugin Berta, Luda Diatchenko, Ru-Rong Ji | |
| 27. | Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing | Jacob Appelbaum, April E. Price, Kaori Oda, Joy Zhang, Wai-Hang Leung, Giacomo Tampella, Dong Xia, Pauline P.L. So, Sarah K. Hilton, Claudya Evandy, Semanti Sarkar, Unja Martin, Anne-Rachel Krostag, Marissa Leonardi, Daniel E. Zak, Rachael Logan, Paula Lewis, Secil Franke-Welch, Njabulo Ngwenyama, Michael Fitzgerald, Niklas Tulberg, Stephanie Rawlings-Rhea, Rebecca A. Gardner, Kyle Jones, Angelica Sanabria, William Crago, John Timmer, Andrew Hollands, Brendan Eckelman, Sanela Bilic, Jim Woodworth, Adam Lamble, Philip D. Gregory, Jordan Jarjour, Mark Pogson, Joshua A. Gustafson, Alexander Astrakhan, Michael C. Jensen | |
更新于 4 分钟前
近期历史最近 100 条记录
| 2024-05-02 | A Laing distal myopathy–associated proline substitution in the β-myosin rod perturbs myosin cross-bridging activity | Massimo Buvoli, Genevieve C.K. Wilson, Ada Buvoli, Jack F. Gugel, Abbi Hau, Carsten G. Bönnemann, Carmen Paradas, David M. Ryba, Kathleen C. Woulfe, Lori A. Walker, Tommaso Buvoli, Julien Ochala, Leslie A. Leinwand | |
| 2024-05-02 | Complement regulation in the eye: implications for age-related macular degeneration | Georgia A. Wilke, Rajendra S. Apte | |
| 2024-05-02 | Cirbp suppression compromises DHODH-mediated ferroptosis defense and attenuates hypothermic cardioprotection in an aged donor transplantation model | Yifan Zhu, Chenyu Jiang, Jian He, Chen He, Xingliang Zhou, Xu Huang, Yi Shen, Liwei Wu, Yongnan Li, Bei Feng, Yi Yan, Jun Li, Hao Zhang, Yiwei Liu | |
| 2024-05-02 | Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling | Emma L. Robinson, Charles A. Tharp, Rushita A. Bagchi, Timothy A. McKinsey | |
| 2024-05-02 | Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses | Fan Huang, Christophe Gonçalves, Margarita Bartish, Joelle Rémy-Sarrazin, Mark E. Issa, Brendan Cordeiro, Qianyu Guo, Audrey Emond, Mikhael Attias, William Yang, Dany Plourde, Jie Su, Marina Godoy Gimeno, Yao Zhan, Alba Galán, Tomasz Rzymski, Milena Mazan | |
| 2024-05-02 | Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation | Theresa Failer, Michael Amponsah-Offeh, Aleš Neuwirth, Ioannis Kourtzelis, Pallavi Subramanian, Peter Mirtschink, Mirko Peitzsch, Klaus Matschke, Sems M. Tugtekin, Tetsuhiro Kajikawa, Xiaofei Li, Anne Steglich, Florian Gembardt, Annika C. Wegner, Christia | |
| 2024-05-02 | CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication | Pablo Tebas, Julie K. Jadlowsky, Pamela A. Shaw, Lifeng Tian, Erin Esparza, Andrea L. Brennan, Sukyung Kim, Soe Yu Naing, Max W. Richardson, Ashley N. Vogel, Colby R. Maldini, Hong Kong, Xiaojun Liu, Simon F. Lacey, Anya M. Bauer, Felicity Mampe, Lee P. R | |
| 2024-05-02 | Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae | Aaron L. Hecht, Lisa C. Harling, Elliot S. Friedman, Ceylan Tanes, Junhee Lee, Jenni Firrman, Fuhua Hao, Vincent Tu, LinShu Liu, Andrew D. Patterson, Kyle Bittinger, Mark Goulian, Gary D. Wu | |
| 2024-05-02 | A therapeutic leap: how myosin inhibitors moved from cardiac interventions to skeletal muscle myopathy solutions | Julius Bogomolovas, Ju Chen | |
| 2024-05-02 | A step closer to understanding how a diet high in simple carbohydrates may cause dysbiosis | Shrinivas Bishu, John Y. Kao | |
| 2024-05-02 | Therapeutic vaccines for herpesviruses | Jeffrey I. Cohen | |
| 2024-05-02 | Adult and neonatal models of chemogenetic heart failure caused by oxidative stress | Fotios Spyropoulos, Apabrita Ayan Das, Markus Waldeck-Weiermair, Shambhu Yadav, Arvind K. Pandey, Ruby Guo, Taylor A. Covington, Venkata Thulabandu, Kosmas Kosmas, Benjamin Steinhorn, Mark A. Perrella, Xiaoli Liu, Helen Christou, Thomas Michel | |
| 2024-05-02 | IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis | Yukun Guan, Brandon Peiffer, Dechun Feng, Maria A. Parra, Yang Wang, Yaojie Fu, Vijay H. Shah, Andrew M. Cameron, Zhaoli Sun, Bin Gao | |
| 2024-05-02 | Life-saving effect of pulmonary surfactant in premature babies | J. Usha Raj, Richard D. Bland, Jahar Bhattacharya, Marlene Rabinovitch, Michael A. Matthay | |
| 2024-05-02 | BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system | Sabine Schneider, Jessica B. Anderson, Rebecca P. Bradley, Katherine Beigel, Christina M. Wright, Beth A. Maguire, Guang Yan, Deanne M. Taylor, J. William Harbour, Robert O. Heuckeroth | |
| 2024-05-02 | Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles | Peter Ruzanov, Valentina Evdokimova, Manideep C. Pachva, Alon Minkovich, Zhenbo Zhang, Sofya Langman, Hendrik Gassmann, Uwe Thiel, Marija Orlic-Milacic, Syed H. Zaidi, Vanya Peltekova, Lawrence E. Heisler, Manju Sharma, Michael E. Cox, Trevor D. McKee, Ma | |
| 2024-05-02 | Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality | Jeremy P. Gygi, Cole Maguire, Ravi K. Patel, Pramod Shinde, Anna Konstorum, Casey P. Shannon, Leqi Xu, Annmarie Hoch, Naresh Doni Jayavelu, Elias K. Haddad, IMPACC Network, Elaine F. Reed, Monica Kraft, Grace A. McComsey, Jordan P. Metcalf, Al Ozonoff, De | |
| 2024-05-02 | A pipeline for senolytics | Sundeep Khosla | |
| 2024-05-02 | Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction | Kyle Vaccaro, Juliet Allen, Troy W. Whitfield, Asaf Maoz, Sarah Reeves, José Velarde, Dian Yang, Anna Meglan, Juliano Ribeiro, Jasmine Blandin, Nicole Phan, George W. Bell, Aaron N. Hata, Kipp Weiskopf | |
| 2024-05-02 | Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain | Sonny R. Elizaldi, Chase E. Hawes, Anil Verma, Yashavanth Shaan Lakshmanappa, Ashok R. Dinasarapu, Brent T. Schlegel, Dhivyaa Rajasundaram, Jie Li, Blythe P. Durbin-Johnson, Zhong-Min Ma, Pabitra B. Pal, Danielle Beckman, Sean Ott, Reben Raeman, Jeffrey L | |
| 2024-05-02 | An in vivo screening platform identifies senolytic compounds that target p16INK4a+ fibroblasts in lung fibrosis | Jin Young Lee, Nabora S. Reyes, Supriya Ravishankar, Minqi Zhou, Maria Krasilnikov, Christian Ringler, Grace Pohan, Chris Wilson, Kenny Kean-Hooi Ang, Paul J. Wolters, Tatsuya Tsukui, Dean Sheppard, Michelle R. Arkin, Tien Peng | |
| 2024-05-02 | TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation | Hong Li, J. Alyce Bradbury, Matthew L. Edin, Artiom Gruzdev, Huiling Li, Joan P. Graves, Laura M. DeGraff, Fred B. Lih, Chiguang Feng, Erin R. Wolf, Carl D. Bortner, Stephanie J. London, Matthew A. Sparks, Thomas M. Coffman, Darryl C. Zeldin | |
| 2024-05-02 | STINGing away the pain: the role of interferon-stimulated genes | Erick J. Rodriguez-Palma, Heather N. Allen, Rajesh Khanna | |
| 2024-05-02 | Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice | Manon Defaye, Amyaouch Bradaia, Nasser S. Abdullah, Francina Agosti, Mircea Iftinca, Mélissa Delanne-Cuménal, Vanessa Soubeyre, Kristofer Svendsen, Gurveer Gill, Aye Ozmaeian, Nadine Gheziel, Jérémy Martin, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery | |
| 2024-05-02 | Enhancing anticancer activity of macrophages through rational drug combinations | Gordon B. Mills, Marilyne Labrie | |
| 2024-05-02 | Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis | Sangsu Bang, Changyu Jiang, Jing Xu, Sharat Chandra, Aidan McGinnis, Xin Luo, Qianru He, Yize Li, Zilong Wang, Xiang Ao, Marc Parisien, Lorenna Oliveira Fernandes de Araujo, Sahel Jahangiri Esfahani, Qin Zhang, Raquel Tonello, Temugin Berta, Luda Diatchen | |
| 2024-05-02 | Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing | Jacob Appelbaum, April E. Price, Kaori Oda, Joy Zhang, Wai-Hang Leung, Giacomo Tampella, Dong Xia, Pauline P.L. So, Sarah K. Hilton, Claudya Evandy, Semanti Sarkar, Unja Martin, Anne-Rachel Krostag, Marissa Leonardi, Daniel E. Zak, Rachael Logan, Paula Le | |
| 2024-04-16 | Granulocytic myeloid-derived suppressor cell activity during biofilm infection is regulated by a glycolysis/HIF1a axis | Christopher M. Horn, Prabhakar Arumugam, Zachary Van Roy, Cortney E. Heim, Rachel W. Fallet, Blake P. Bertrand, Dhananjay Shinde, Vinai C. Thomas, Svetlana G. Romanova, Tatiana K. Bronich, Curtis W. Hartman, Kevin L. Garvin, Tammy Kielian | |
| 2024-04-16 | CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4 | Siqi Chen, Jie Fan, Ping Xie, Jihae Ahn, Michelle Fernandez, Leah K. Billingham, Jason Miska, Jennifer D. Wu, Derek A. Wainwright, Deyu Fang, Jeffrey A. Sosman, Yong Wan, Yi Zhang, Navdeep S. Chandel, Bin Zhang | |
| 2024-04-16 | Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants | Mengfei Chen, Andrew Pekosz, Jason S. Villano, Wenjuan Shen, Ruifeng Zhou, Heather Kulaga, Zhexuan Li, Amy Smith, Asiana Gurung, Sarah E. Beck, Kenneth W. Witwer, Joseph L. Mankowski, Murugappan Ramanathan Jr, Nicholas R. Rowan, Andrew P. Lane | |
| 2024-04-16 | Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation | Leslie S. Kean, Bruce R. Blazar | |
| 2024-04-16 | 68Ga-FAPI PET imaging monitors response to combined TGF-βR inhibition and immunotherapy in metastatic colorectal cancer | Ke Li, Wei Liu, Hang Yu, Jiwei Chen, Wenxuan Tang, Jianpeng Wang, Ming Qi, Yuyun Sun, Xiaoping Xu, Ji Zhang, Xinxiang Li, Weijian Guo, Xiaoling Li, Shaoli Song, Shuang Tang | |
| 2024-04-16 | A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1 | Ane Korff, Xiaojing Yang, Kevin O’Donovan, Abner Gonzalez, Brett J.W. Teubner, Haruko Nakamura, James Messing, Fen Yang, Alexandre F. Carisey, Yong-Dong Wang, Tushar Patni, Heather Sheppard, Stanislav S. Zakharenko, Yuh Min Chook, J. Paul Taylor, Hong Joo | |
| 2024-04-16 | Reduced incretin effect precedes diabetes development following duodenopancreatectomy in individuals without diabetes | Gianfranco Di Giuseppe, Laura Soldovieri, Gea Ciccarelli, Pietro Manuel Ferraro, Giuseppe Quero, Francesca Cinti, Umberto Capece, Simona Moffa, Enrico Celestino Nista, Antonio Gasbarrini, Andrea Mari, Sergio Alfieri, Vincenzo Tondolo, Alfredo Pontecorvi, | |
| 2024-04-16 | Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes | Nicolas Skuli, Amar J. Majmundar, Bryan L. Krock, Rickson C. Mesquita, Lijoy K. Mathew, Zachary L. Quinn, Anja Runge, Liping Liu, Meeri N. Kim, Jiaming Liang, Steven Schenkel, Arjun G. Yodh, Brian Keith, M. Celeste Simon | |
| 2024-04-16 | MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma | Yao Zhan, Jun Guo, William Yang, Christophe Goncalves, Tomasz Rzymski, Agnieszka Dreas, Eliza Żyłkiewicz, Maciej Mikulski, Krzysztof Brzózka, Aniela Golas, Yan Kong, Meng Ma, Fan Huang, Bonnie Huor, Qianyu Guo, Sabrina Daniela da Silva, Jose Torres, Yutia | |
| 2024-04-16 | An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model | Chenwei Wang, Jiewen Chen, Jingyao Li, Zhihong Xu, Lihong Huang, Qian Zhao, Lei Chen, Xiaolong Liang, Hai Hu, Gang Li, Chengjie Xiong, Bin Wu, Hua You, Danyi Du, Xiaoling Wang, Hongle Li, Zibing Wang, Lin Chen | |
| 2024-04-16 | Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models | Ekjot Kaur, Ritu Agrawal, Rimpy Arun, Vinoth Madhavan, Vivek Srivastava, Dilip Kumar, Pragyan Parimita Rath, Nitin Kumar, Sreekanth Vedagopuram, Nishant Pandey, Swati Priya, Patrick Legembre, Samudrala Gourinath, Avinash Bajaj, Sagar Sengupta | |
| 2024-04-16 | The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers | Carmen Gasca-Capote, Xiaodong Lian, Ce Gao, Isabelle C. Roseto, María Reyes Jiménez-León, Gregory Gladkov, María Inés Camacho-Sojo, Alberto Pérez-Gómez, Isabel Gallego, Luis E. Lopez-Cortes, Sara Bachiller, Joana Vitalle, Mohamed Rafii-El-Idrissi Benhnia, | |
| 2024-04-16 | Central conducting lymphatic anomaly: from bench to bedside | Luciana Daniela Garlisi Torales, Benjamin A. Sempowski, Georgia L. Krikorian, Kristina M. Woodis, Scott M. Paulissen, Christopher L. Smith, Sarah E. Sheppard | |
| 2024-04-16 | Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency | Sarah Aminov, Orsi Giricz, David T. Melnekoff, R. Alejandro Sica, Veronika Polishchuk, Cristian Papazoglu, Bonnie Yates, Hao-Wei Wang, Srabani Sahu, Yanhua Wang, Shanisha Gordon-Mitchell, Violetta V. Leshchenko, Carolina Schinke, Kith Pradhan, Srinivas Al | |
| 2024-04-16 | Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis | Cheng Zhang, Miaomiao Yu, Austin J. Hepperla, Zhao Zhang, Rishi Raj, Hua Zhong, Jin Zhou, Lianxin Hu, Jun Fang, Hongyi Liu, Qian Liang, Liwei Jia, Chengheng Liao, Sichuan Xi, Jeremy M. Simon, Kexin Xu, Zhijie Liu, Yunsun Nam, Payal Kapur, Qing Zhang | |
| 2024-04-16 | VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas | Hyemin Lee, Li Zhuang, Boyi Gan | |
| 2024-04-16 | Oncotherapy resistance explained by Darwinian and Lamarckian models | Yogen Saunthararajah | |
| 2024-04-16 | Capillary malformations | Adrienne M. Hammill, Elisa Boscolo | |
| 2024-04-16 | VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis | Melissa M. Wolf, Matthew Z. Madden, Emily N. Arner, Jackie E. Bader, Xiang Ye, Logan Vlach, Megan L. Tigue, Madelyn D. Landis, Patrick B. Jonker, Zaid Hatem, KayLee K. Steiner, Dakim K. Gaines, Bradley I. Reinfeld, Emma S. Hathaway, Fuxue Xin, M. Noor Tan | |
| 2024-04-16 | Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia | Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Mark W. Zimmerman, Thomas Eder, Diaaeldin I. Abdallah, Barbara Maurer, Christina Wagner, Susann Schönefeldt, Katrin Spirk, Alexander Pichler, Tea Pemovska, Carmen Schweicker, Danie | |
| 2024-04-16 | Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals | Jessica N. Peel, Rui Yang, Tom Le Voyer, Adrian Gervais, Jérémie Rosain, Paul Bastard, Anish Behere, Axel Cederholm, Aaron Bodansky, Yoann Seeleuthner, Clément Conil, Jing-Ya Ding, Wei-Te Lei, Lucy Bizien, Camille Soudee, Mélanie Migaud, Masato Ogishi, Ah | |
| 2024-04-16 | A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis | Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina | |
| 2024-04-16 | Ectopic expression of the transcription factor ONECUT3 drives a complex karyotype in myelodysplastic syndromes | Yingwan Luo, Xiaomin Feng, Wei Lang, Weihong Xu, Wei Wang, Chen Mei, Li Ye, Shuanghong Zhu, Lu Wang, Xinping Zhou, Huimin Zeng, Liya Ma, Yanling Ren, Jie Jin, Rongzhen Xu, Gang Huang, Hongyan Tong | |
| 2024-04-16 | T antigen–specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma | Ulla Kring Hansen, Candice D. Church, Ana Micaela Carnaz Simões, Marcus Svensson Frej, Amalie Kai Bentzen, Siri A. Tvingsholm, Jürgen C. Becker, Steven P. Fling, Nirasha Ramchurren, Suzanne L. Topalian, Paul T. Nghiem, Sine Reker Hadrup | |
| 2024-04-16 | Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL | Nicolas Dupré, Florian Gueniot, Valérie Domenga-Denier, Virginie Dubosclard, Christelle Nilles, David Hill-Eubanks, Christelle Morgenthaler-Roth, Mark T. Nelson, Céline Keime, Lydia Danglot, Anne Joutel | |
| 2024-04-16 | Complement C3 and marginal zone B cells promote IgG-mediated enhancement of RBC alloimmunization in mice | Arijita Jash, Thomas Pridmore, James B. Collins, Ariel M. Hay, Krystalyn E. Hudson, Chance John Luckey, James C. Zimring | |
| 2024-04-16 | Polyomavirus-positive Merkel cell carcinoma: the beginning of the beginning | Michael K. Wong, Cassian Yee | |
| 2024-04-16 | Infantile hemangioma: the common and enigmatic vascular tumor | Annegret Holm, John B. Mulliken, Joyce Bischoff | |
| 2024-04-02 | Howard Chang receives the 2024 ASCI/Stanley J. Korsmeyer Award | Lisa R. Conti | |
| 2024-04-02 | The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia | Nicole Calakos, Zachary F. Caffall | |
| 2024-04-02 | IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation | Ping Zhang, Peter Fleming, Christopher E. Andoniou, Olivia G. Waltner, Shruti S. Bhise, Jose Paulo Martins, Benjamin A. McEnroe, Valentina Voigt, Sheridan Daly, Rachel D. Kuns, Adaeze P. Ekwe, Andrea S. Henden, Alda Saldan, Stuart Olver, Antiopi Varelias, | |
| 2024-04-02 | mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b | Kahealani Uehara, Won Dong Lee, Megan Stefkovich, Dipsikha Biswas, Dominic Santoleri, Anna Garcia Whitlock, William Quinn III, Talia Coopersmith, Kate Townsend Creasy, Daniel J. Rader, Kei Sakamoto, Joshua D. Rabinowitz, Paul M. Titchenell | |
| 2024-04-02 | A conversation with Elias Zerhouni | Ushma S. Neill | |
| 2024-04-02 | Pandemics past, present, and future: progress and persistent risks | Arturo Casadevall | |
| 2024-04-02 | Surviving without BRCA2: MLH1 gets R-looped in to curtail genomic instability | Neil Johnson | |
| 2024-04-02 | OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage | Volodymyr Tsvilovskyy, Roger Ottenheijm, Ulrich Kriebs, Aline Schütz, Kalliope Nina Diakopoulos, Archana Jha, Wolfgang Bildl, Angela Wirth, Julia Böck, Dawid Jaślan, Irene Ferro, Francisco J. Taberner, Olga Kalinina, Staffan Hildebrand, Ulrich Wissenbach, | |
| 2024-04-02 | Tissue-specific reprogramming leads to angiogenic neutrophil specialization and tumor vascularization in colorectal cancer | Triet M. Bui, Lenore K. Yalom, Edward Ning, Jessica M. Urbanczyk, Xingsheng Ren, Caroline J. Herrnreiter, Jackson A. Disario, Brian Wray, Matthew J. Schipma, Yuri S. Velichko, David P. Sullivan, Kouki Abe, Shannon M. Lauberth, Guang-Yu Yang, Parambir S. D | |
| 2024-04-02 | Mismatch repair protein MLH1 suppresses replicative stress in BRCA2-deficient breast tumors | Satheesh K. Sengodan, Xiaoju Hu, Vaishnavi Peddibhotla, Kuppusamy Balamurugan, Alexander Y. Mitrophanov, Lois McKennett, Suhas S. Kharat, Rahul Sanawar, Vinod Kumar Singh, Mary E. Albaugh, Sandra S. Burkett, Yongmei Zhao, Bao Tran, Tyler Malys, Esta Stern | |
| 2024-04-02 | Increasing histone acetylation improves sociability and restores learning and memory in KAT6B-haploinsufficient mice | Maria I. Bergamasco, Hannah K. Vanyai, Alexandra L. Garnham, Niall D. Geoghegan, Adam P. Vogel, Samantha Eccles, Kelly L. Rogers, Gordon K. Smyth, Marnie E. Blewitt, Anthony J. Hannan, Tim Thomas, Anne K. Voss | |
| 2024-04-02 | Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage | Viktor Arnhold, Winston Y. Chang, Suze A. Jansen, Govindarajan Thangavelu, Marco Calafiore, Paola Vinci, Ya-Yuan Fu, Takahiro Ito, Shuichiro Takashima, Anastasiya Egorova, Jason Kuttiyara, Adam Perlstein, Marliek van Hoesel, Chen Liu, Bruce R. Blazar, Car | |
| 2024-04-02 | A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults | Alfred B. Tiono, Jordan L. Plieskatt, Alphonse Ouedraogo, Ben Idriss Soulama, Kazutoyo Miura, Edith C. Bougouma, Mohammad Naghizadeh, Aissata Barry, Jean Baptist B. Yaro, Sem Ezinmegnon, Noelie Henry, Ebenezer Addo Ofori, Bright Adu, Susheel K. Singh, Aug | |
| 2024-04-02 | Hepatocyte-specific CCAAT/enhancer binding protein α restricts liver fibrosis progression | Tingting Yan, Nana Yan, Yangliu Xia, Vorthon Sawaswong, Xinxin Zhu, Henrique Bregolin Dias, Daisuke Aibara, Shogo Takahashi, Keisuke Hamada, Yoshifumi Saito, Guangming Li, Hui Liu, Hualong Yan, Thomas J. Velenosi, Kristopher W. Krausz, Jing Huang, Shioko | |
| 2024-04-02 | Protective hepatocyte signals restrain liver fibrosis in metabolic dysfunction–associated steatohepatitis | Marcella Steffani, Yana Geng, Utpal B. Pajvani, Robert F. Schwabe | |
| 2024-04-02 | Soluble immune-checkpoint factors: a potential immunotherapy biomarker | Aaron C. Tan, Sarah L. Cook, Mustafa Khasraw | |
| 2024-04-02 | Anti–PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers | Karsten Eichholz, Yoshinori Fukazawa, Christopher W. Peterson, Francoise Haeseleer, Manuel Medina, Shelby Hoffmeister, Derick M. Duell, Benjamin D. Varco-Merth, Sandra Dross, Haesun Park, Caralyn S. Labriola, Michael K. Axthelm, Robert D. Murnane, Jeremy | |
| 2024-04-02 | The road to refractory graft-versus-host disease is paved with good intentions | Daniel North, Ronjon Chakraverty | |
| 2024-04-02 | Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis | Gopinath Prakasam, Akhilesh Mishra, Alana Christie, Jeffrey Miyata, Deyssy Carrillo, Vanina T. Tcheuyap, Hui Ye, Quyen N. Do, Yunguan Wang, Oscar Reig Torras, Ramesh Butti, Hua Zhong, Jeffrey Gagan, Kevin B. Jones, Thomas J. Carroll, Zora Modrusan, Steffe | |
| 2024-04-02 | The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice | Victoria Bryson, Chaojian Wang, Zirui Zhou, Kavisha Singh, Noah Volin, Eda Yildirim, Paul Rosenberg | |
| 2024-04-02 | MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells | Rutger J. Röring, Priya A. Debisarun, Javier Botey-Bataller, Tsz Kin Suen, Özlem Bulut, Gizem Kilic, Valerie A.C.M. Koeken, Andrei Sarlea, Harsh Bahrar, Helga Dijkstra, Heidi Lemmers, Katharina L. Gössling, Nadine Rüchel, Philipp N. Ostermann, Lisa Müller | |
| 2024-04-02 | HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial | Zheqi Li, Otto Metzger Filho, Giuseppe Viale, Patrizia dell’Orto, Leila Russo, Marie-Anne Goyette, Avni Kamat, Denise A. Yardley, Vandana Gupta Abramson, Carlos L. Arteaga, Laura M. Spring, Kami Chiotti, Carol Halsey, Adrienne G. Waks, Tari A. King, Susan | |
| 2024-04-02 | Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade | Hidetoshi Hayashi, Kenji Chamoto, Ryusuke Hatae, Takashi Kurosaki, Yosuke Togashi, Kazuya Fukuoka, Megumi Goto, Yasutaka Chiba, Shuta Tomida, Takayo Ota, Koji Haratani, Takayuki Takahama, Junko Tanizaki, Takeshi Yoshida, Tsutomu Iwasa, Kaoru Tanaka, Masay | |
| 2020-03-13 | Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy | Xia Liu, Daniel F. Hoft, Guangyong Peng | |
| 2020-03-13 | The multifaceted role of ischemia/reperfusion in sickle cell anemia | Robert P. Hebbel, John D. Belcher, Gregory M. Vercellotti | |
| 2020-03-13 | Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α | M. Ahsan Siraj, Dhanwantee Mundil, Sanja Beca, Abdul Momen, Eric A. Shikatani, Talat Afroze, Xuetao Sun, Ying Liu, Siavash Ghaffari, Warren Lee, Michael B. Wheeler, Gordon Keller, Peter Backx, Mansoor Husain | |
| 2020-03-13 | A conversation with Barbara Kahn | Ushma S. Neill | |
| 2020-03-13 | Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease | Annelise M. Poss, J. Alan Maschek, James E. Cox, Benedikt J. Hauner, Paul N. Hopkins, Steven C. Hunt, William L. Holland, Scott A. Summers, Mary C. Playdon | |
| 2020-03-13 | Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability | Lin Li, Mohammad Ghorbani, Monika Weisz-Hubshman, Justine Rousseau, Isabelle Thiffault, Rhonda E. Schnur, Catherine Breen, Renske Oegema, Marjan M.M. Weiss, Quinten Waisfisz, Sara Welner, Helen Kingston, Jordan A. Hills, Elles M.J. Boon, Lina Basel-Salmon | |
| 2020-03-13 | IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes | Takashi K. Satoh, Mark Mellett, Barbara Meier-Schiesser, Gabriele Fenini, Atsushi Otsuka, Hans-Dietmar Beer, Tamara Rordorf, Julia-Tatjana Maul, Jürg Hafner, Alexander A. Navarini, Emmanuel Contassot, Lars E. French | |
| 2020-03-13 | CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment | Shi Yong Neo, Ying Yang, Julien Record, Ran Ma, Xinsong Chen, Ziqing Chen, Nicholas P. Tobin, Emily Blake, Christina Seitz, Ron Thomas, Arnika Kathleen Wagner, John Andersson, Jana de Boniface, Jonas Bergh, Shannon Murray, Evren Alici, Richard Childs, Mar | |
| 2020-03-13 | When bugs and drugs conspire: driving acneiform skin toxicity | Allison C. Billi, Mrinal K. Sarkar, Johann E. Gudjonsson | |
| 2020-03-13 | A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target | Zachary T. Freeman, Thomas R. Nirschl, Daniel H. Hovelson, Robert J. Johnston, John J. Engelhardt, Mark J. Selby, Christina M. Kochel, Ruth Y. Lan, Jingyi Zhai, Ali Ghasemzadeh, Anuj Gupta, Alyza M. Skaist, Sarah J. Wheelan, Hui Jiang, Alexander T. Pearso | |
| 2020-03-13 | Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease | Gordon I. Smith, Mahalakshmi Shankaran, Mihoko Yoshino, George G. Schweitzer, Maria Chondronikola, Joseph W. Beals, Adewole L. Okunade, Bruce W. Patterson, Edna Nyangau, Tyler Field, Claude B. Sirlin, Saswata Talukdar, Marc K. Hellerstein, Samuel Klein | |
| 2020-03-13 | A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia | Mark S. Williams, Fabio M.R. Amaral, Fabrizio Simeoni, Tim C.P. Somervaille | |
| 2020-03-13 | Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation | Simon McArthur, Gaëtan Juban, Thomas Gobbetti, Thibaut Desgeorges, Marine Theret, Julien Gondin, Juliana E. Toller-Kawahisa, Chris P. Reutelingsperger, Bénédicte Chazaud, Mauro Perretti, Rémi Mounier | |
| 2020-03-13 | Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase–deficient mice | Chloe Santos, Yun Jin Pai, M. Raasib Mahmood, Kit-Yi Leung, Dawn Savery, Simon N. Waddington, Andrew J. Copp, Nicholas D.E. Greene | |
| 2020-03-13 | How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer | Lena Claesson-Welsh | |
| 2020-03-13 | Underglycosylated prion protein modulates plaque formation in the brain | Jason C. Bartz | |
| 2020-03-13 | Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease | Alejandro M. Sevillano, Patricia Aguilar-Calvo, Timothy D. Kurt, Jessica A. Lawrence, Katrin Soldau, Thu H. Nam, Taylor Schumann, Donald P. Pizzo, Sofie Nyström, Biswa Choudhury, Hermann Altmeppen, Jeffrey D. Esko, Markus Glatzel, K. Peter R. Nilsson, Chr | |
| 2020-03-13 | Linear ubiquitin assembly complex regulates lung epithelial–driven responses during influenza infection | Patricia L. Brazee, Luisa Morales-Nebreda, Natalia D. Magnani, Joe G.N. Garcia, Alexander V. Misharin, Karen M. Ridge, G.R. Scott Budinger, Kazuhiro Iwai, Laura A. Dada, Jacob I. Sznajder | |
| 2020-03-13 | Breaking through the surface: more to learn about lipids and cardiovascular disease | Justin B. Echouffo-Tcheugui, Mohit Jain, Susan Cheng | |
| 2020-03-13 | Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS | Kaitlin Weskamp, Elizabeth M. Tank, Roberto Miguez, Jonathon P. McBride, Nicolás B. Gómez, Matthew White, Ziqiang Lin, Carmen Moreno Gonzalez, Andrea Serio, Jemeen Sreedharan, Sami J. Barmada | |
| 2020-03-13 | Stable ischemic heart disease: how to keep it that way | Thorsten M. Leucker, Steven P. Schulman, Gary Gerstenblith | |
| 2020-03-13 | Oral immunotherapy tolerizes mice to enzyme replacement therapy for Morquio A syndrome | Angela C. Sosa, Barbara Kariuki, Qi Gan, Alan P. Knutsen, Clifford J. Bellone, Miguel A. Guzmán, Luis A. Barrera, Shunji Tomatsu, Anil K. Chauhan, Eric Armbrecht, Adriana M. Montaño | |
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