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近期历史最近 100 条记录

2024-04-18 Erratum for the Research Article “Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide” by M. Jan et al. | Science Translational Medicine
2024-04-18 Nociceptor spontaneous activity is responsible for fragmenting non–rapid eye movement sleep in mouse models of neuropathic pain | Science Translational Medicine
2024-04-18 Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice | Science Translational Medicine
2024-04-18 Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human | Science Translational Medicine
2024-04-18 Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology | Science Translational Medicine
2024-04-18 Deep learning assists detection of esophageal cancer and precursor lesions in a prospective, randomized controlled study | Science Translational Medicine
2024-04-11 BCR signaling is required for posttransplant lymphoproliferative disease in immunodeficient mice receiving human B cells | Science Translational Medicine
2024-04-11 Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma | Science Translational Medicine
2024-04-11 A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury | Science Translational Medicine
2024-04-11 Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis | Science Translational Medicine
2024-04-11 Contribution of the patient microbiome to surgical site infection and antibiotic prophylaxis failure in spine surgery | Science Translational Medicine
2024-04-11 Where do the pathogens that cause surgical site infections come from? | Science Translational Medicine
2024-04-04 Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease | Science Translational Medicine
2024-04-04 Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease | Science Translational Medicine
2024-04-04 Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model | Science Translational Medicine
2024-04-04 TSPAN8+ myofibroblastic cancer–associated fibroblasts promote chemoresistance in patients with breast cancer | Science Translational Medicine
2024-04-04 Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates | Science Translational Medicine
2024-03-28 Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis | Science Translational Medicine
2024-03-28 The gut microbiota posttranslationally modifies IgA1 in autoimmune glomerulonephritis | Science Translational Medicine
2024-03-28 Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories | Science Translational Medicine
2024-03-28 Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques | Science Translational Medicine
2024-03-28 Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al. | Science Translational Medicine
2023-09-01 Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy | Science Translational Medicine
2023-08-31 A blood-based marker of mitochondrial DNA damage in Parkinson’s disease | Science Translational Medicine
2023-08-31 An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models | Science Translational Medicine
2023-08-31 Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate | Science Translational Medicine
2023-08-31 The anti-CD40L monoclonal antibody AT-1501 promotes islet and kidney allograft survival and function in nonhuman primates | Science Translational Medicine
2023-08-31 TREM1 activation of myeloid cells promotes antitumor immunity | Science Translational Medicine
2023-08-24 FcγRIIB expressed on CD8+ T cells limits responsiveness to PD-1 checkpoint inhibition in cancer | Science Translational Medicine
2023-08-24 A complement atlas identifies interleukin-6–dependent alternative pathway dysregulation as a key druggable feature of COVID-19 | Science Translational Medicine
2023-08-24 The RSVPreF3-AS01 vaccine elicits broad neutralization of contemporary and antigenically distant respiratory syncytial virus strains | Science Translational Medicine
2023-08-24 Targeting sulfation-dependent mechanoreciprocity between matrix and osteoblasts to mitigate bone loss | Science Translational Medicine
2023-08-17 NKG2D-CAR T cells eliminate senescent cells in aged mice and nonhuman primates | Science Translational Medicine
2023-08-17 Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination | Science Translational Medicine
2023-08-17 Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer | Science Translational Medicine
2023-08-17 Endothelial FoxM1 reactivates aging-impaired endothelial regeneration for vascular repair and resolution of inflammatory lung injury | Science Translational Medicine
2023-08-17 Erratum for the Review “Insights into dengue immunity from vaccine trials” | Science Translational Medicine
2023-08-10 Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome | Science Translational Medicine
2023-08-10 Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts | Science Translational Medicine
2023-08-10 A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis | Science Translational Medicine
2023-08-10 Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens | Science Translational Medicine
2023-08-10 The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons | Science Translational Medicine
2023-08-03 Single-cell transcriptomics identifies prothymosin α restriction of HIV-1 in vivo | Science Translational Medicine
2023-08-03 Gut-licensed β7+ CD4+ T cells contribute to progressive retinal ganglion cell damage in glaucoma | Science Translational Medicine
2023-08-03 Proregenerative extracellular matrix hydrogel mitigates pathological alterations of pelvic skeletal muscles after birth injury | Science Translational Medicine
2023-08-03 Alternative splicing of CEACAM1 by hypoxia-inducible factor–1α enhances tolerance to hepatic ischemia in mice and humans | Science Translational Medicine
2023-08-03 Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers | Science Translational Medicine
2023-08-03 Measuring translational research impact requires reaching beyond current metrics | Science Translational Medicine
2023-07-27 Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology | Science Translational Medicine
2023-07-27 Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging | Science Translational Medicine
2023-07-27 Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes | Science Translational Medicine
2023-07-27 Signatures of AAV-2 immunity are enriched in children with severe acute hepatitis of unknown etiology | Science Translational Medicine
2023-07-27 Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse | Science Translational Medicine
2023-07-27 Targeting electrochemical communication between neurons and cancer | Science Translational Medicine
2023-07-20 Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma | Science Translational Medicine
2023-07-20 Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life | Science Translational Medicine
2023-07-20 Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma | Science Translational Medicine
2023-07-20 Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity | Science Translational Medicine
2023-07-20 Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment | Science Translational Medicine
2023-07-13 RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration | Science Translational Medicine
2023-07-13 Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states | Science Translational Medicine
2023-07-13 Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection | Science Translational Medicine
2023-07-13 PTEN deficiency facilitates gemcitabine efficacy in cancer by modulating the phosphorylation of PP2Ac and DCK | Science Translational Medicine
2023-07-13 Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes | Science Translational Medicine
2023-07-13 Insights into dengue immunity from vaccine trials | Science Translational Medicine
2023-07-06 Dysregulated IFN-γ signals promote autoimmunity in STAT1 gain-of-function syndrome | Science Translational Medicine
2023-07-06 Erratum for the Research Article “Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide” by M. Jan et al. | Science Translational Medicine
2023-07-06 Measuring anti-islet autoimmunity in mouse and human by profiling peripheral blood antigen-specific CD4 T cells | Science Translational Medicine
2023-07-06 Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease | Science Translational Medicine
2023-07-06 Precision functional MRI mapping reveals distinct connectivity patterns for depression associated with traumatic brain injury | Science Translational Medicine
2023-07-06 Broadly neutralizing antibody treatment maintained HIV suppression in children with favorable reservoir characteristics in Botswana | Science Translational Medicine
2023-07-06 Broadly neutralizing antibodies: “The next thing” to treat children with HIV? | Science Translational Medicine
2023-06-29 Long-acting refillable nanofluidic implant confers protection against SHIV infection in nonhuman primates | Science Translational Medicine
2023-06-29 Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma | Science Translational Medicine
2023-06-29 Delivery of gene therapy through CSF conduit to rescue hearing in adult mice bookofjoe
2023-06-29 Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates | Science Translational Medicine
2023-06-29 PET imaging of TREM1 identifies CNS-infiltrating myeloid cells in a mouse model of multiple sclerosis | Science Translational Medicine
2023-06-29 Erratum for the Research Article “Aberrant activation of m6A demethylase FTO renders HIF2αlow/– clear cell renal cell carcinoma sensitive to BRD9 inhibitors” by C. Zhang et al. | Science Translational Medicine
2023-06-22 An integrated isothermal nucleic acid amplification test to detect HPV16 and HPV18 DNA in resource-limited settings | Science Translational Medicine
2023-06-22 BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA-mutant ovarian cancer | Science Translational Medicine
2023-06-22 High-resolution daily profiles of tissue adrenal steroids by portable automated collection | Science Translational Medicine
2023-06-22 An adenoviral-vectored vaccine confers seroprotection against capsular group B meningococcal disease | Science Translational Medicine
2023-06-22 An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor | Science Translational Medicine
2023-06-22 Closing the loop on adrenal health, dysfunction, and disease | Science Translational Medicine
2023-06-15 Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease | Science Translational Medicine
2023-06-15 Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts | Science Translational Medicine
2023-06-15 Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody | Science Translational Medicine
2023-06-15 Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis | Science Translational Medicine
2023-06-15 Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms | Science Translational Medicine
2023-06-08 Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer | Science Translational Medicine
2023-06-08 Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration | Science Translational Medicine
2023-06-08 Neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma | Science Translational Medicine
2023-06-08 Preventing skin toxicities induced by EGFR inhibitors by topically blocking drug-receptor interactions | Science Translational Medicine
2023-06-08 Impact of prior dengue virus infection on Zika virus infection during pregnancy in marmosets | Science Translational Medicine
2023-06-08 Senescent cells as thermostats of antitumor immunity | Science Translational Medicine
2023-06-01 Constitutive IL-1RA production by modified immune cells protects against IL-1–mediated inflammatory disorders | Science Translational Medicine
2023-06-01 PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production | Science Translational Medicine
2023-06-01 Inhibition of FGF23 is a therapeutic strategy to target hematopoietic stem cell niche defects in β-thalassemia | Science Translational Medicine
2023-06-01 Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas | Science Translational Medicine
2023-06-01 Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis | Science Translational Medicine

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